OUR EXPERIENCE

The experienced GMP manufacturing and R&D teams at Small New World Laboratories guarantee a production process to pharmaceutical standards, and provide the scientific bases and knowledge for further improvement and advancement of this novel biological therapeutic that has the potential to become a versatile platform technology for the development of novel future therapeutics strategies.

OUR REFERENCES

Jenner F, et al. 2023:   Evaluation of the Potential of Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles to Improve Rotator Cuff Healing: A Pilot Ovine Study. Am J Sports Med.  PMID: 36645050

Romanelli P, et al. 2022:  Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury. Front Cell Neurosci.  PMID: 35046776 

Warnecke A, et al. 2021: First-in-human intracochlear application of human stromal cell-derived extracellular vesicles. J Extracell Vesicles.  PMID: 34136108 

Gimona M, et al. 2021: Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles. Cytotherapy. PMID: 33934807

Warnecke A,et al. 2020: Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo. Clin Transl Med.  PMID: 33377658 

Rohde E, Pachler K, Gimona M. 2020: Manufacturing and characterization of extracellular vesicles from umbilical cord-derived mesenchymal stromal cells for clinical testing. Cytotherapy.  PMID: 30979664 

Lener T, Gimona M, et al. 2015: Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper. J Extracell Vesicles. PMID: 26725829